SalaryData

Registered Nurse Salary in Missouri

Based on 76K+ workers in Missouri

Data year: 2025 · Last updated: October 2026

Median Annual Salary (MO)

$81,780

$39.32/hr

vs National Average

$94,098

-13.1% vs national median

Salary Range (10th–90th)

$63K – $104K

76K employed in Missouri

The median Registered Nurse salary in Missouri stands at $81,780 annually, with a typical range from $63,230 to $104,390. This figure places the average compensation for these essential healthcare professionals 13% below the national average, though there are currently 76,310 Registered Nurses employed across the state.

Several factors can influence the Registered Nurse salary in Missouri, including the specific geographic location within the state, the type of healthcare facility (e.g., hospital, clinic, long-term care), years of experience, and any specialized certifications or advanced degrees held by the nurse. These elements contribute to the observed salary variations.

Salary Distribution — Registered Nurse in Missouri

Registered Nurse (MO) salary percentiles
PercentileAnnual Salary
10th percentile$63,230
25th percentile$76,050
Median (50th percentile)$81,780
75th percentile$98,560
90th percentile$104,390

Top-Paying Industries for Registered Nurse (U.S.)

Which industries pay Registered Nurses the most — nationwide figures (industry-level data is not available by state). Registered Nurses in Missouri tend to follow these industry patterns.

Industry (U.S.)Median SalaryEmployed (U.S.)
Government (excl. schools, hospitals & USPS)$110,780170K
Management of Companies and Enterprises$100,01023K
Health Care and Social Assistance$97,6602.9M
Information$97,430590
Utilities$95,28070

Source: U.S. BLS OEWS National Industry-Specific estimates, May 2025. National figures (not state-specific).

Historical Salary Trend — Registered Nurse in Missouri vs National

Historical Registered Nurse salary trend in Missouri
YearMedian Salary (Missouri)
2022$71,460
2023$77,190
2024$79,770
2025$81,780
2026 (projected)$83,841

The latest year is a projection based on recent wage trends — BLS has not yet released that year’s data.

Historical salary trend for Registered Nurse in Missouri
YearMissouri MedianNational Median
2022$71,460$81,890
2023$77,190$86,652
2024$79,770$90,458
2025$81,780$94,098
2026 (projected)$83,841$96,469

Registered Nurse Salary by Experience Level in Missouri

Registered Nurse salary by experience level in Missouri
Experience LevelYearsMedian Annual Salary
Junior0-2 yrs$76,050
Mid-level3-5 yrs$81,780
Senior6-9 yrs$98,560
Staff / Lead10+ yrs$104,390

Registered Nurse Salary in Other States

Related Registered Nurse Salaries in Missouri

How other high-demand occupations in Missouri compare to Registered Nurse ($81,780 median).

OccupationMedian Salaryvs Registered NurseHourly
Cardiologist in MO$648,070+692.5%$311.57/hr
Emergency Medicine Physician in MO$456,280+457.9%$219.37/hr
Psychiatrist in MO$312,680+282.3%$150.33/hr
Nurse Anesthetist in MO$242,630+196.7%$116.65/hr
Pediatrician in MO$223,910+173.8%$107.65/hr
Internal Medicine Physician in MO$216,570+164.8%$104.12/hr
Dentist in MO$204,960+150.6%$98.54/hr
Family Medicine Physician in MO$171,180+109.3%$82.30/hr
Pharmacist in MO$137,610+68.3%$66.16/hr
Physician Assistant in MO$135,130+65.2%$64.97/hr
Optometrist in MO$133,810+63.6%$64.33/hr
Nurse Midwife in MO$130,220+59.2%$62.61/hr

Frequently Asked Questions

What is the average salary for a Registered Nurse in Missouri?

The median salary for a Registered Nurse in Missouri is $81,780 per year, which translates to approximately $39 per hour. This median figure indicates that half of all Registered Nurses in the state earn more than this amount, and half earn less.

How does the Registered Nurse salary in Missouri compare to the national average?

Registered Nurse salaries in Missouri are 13.1% lower than the national average. This means that, on average, RNs in Missouri earn less than their counterparts across the United States.

What is the salary range for Registered Nurses in Missouri?

The salary range for Registered Nurses in Missouri generally falls between $63,230 and $104,390 annually. This wide range reflects differences in experience, location within the state, and specific healthcare settings.

How many Registered Nurses are employed in Missouri?

There are approximately 76,310 Registered Nurses employed in Missouri. This substantial number highlights the significant demand and presence of RNs within the state's healthcare system.

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