SalaryData

Nurse Practitioner Salary in South Carolina

Based on 6K+ workers in South Carolina

Data year: 2025 · Last updated: October 2026

Median Annual Salary (SC)

$123,290

$59.27/hr

vs National Average

$133,771

-7.8% vs national median

Salary Range (10th–90th)

$97K – $160K

6K employed in South Carolina

The median Nurse Practitioner salary in South Carolina is $123,290 annually. This figure sits 8% below the national average for the profession, with current employment for Nurse Practitioners in the state reaching approximately 5,670 individuals. This data provides a foundational understanding of compensation for these vital healthcare professionals within the Palmetto State.

Several factors can influence the Nurse Practitioner salary in South Carolina. These include years of experience, the specific specialty practiced (such as family medicine or acute care), the size and type of healthcare facility, and geographic location within the state. Negotiating skills and further certifications can also play a significant role in determining an individual's earning potential.

Salary Distribution — Nurse Practitioner in South Carolina

Nurse Practitioner (SC) salary percentiles
PercentileAnnual Salary
10th percentile$97,080
25th percentile$107,930
Median (50th percentile)$123,290
75th percentile$132,220
90th percentile$160,170

Top-Paying Industries for Nurse Practitioner (U.S.)

Which industries pay Nurse Practitioners the most — nationwide figures (industry-level data is not available by state). Nurse Practitioners in South Carolina tend to follow these industry patterns.

Industry (U.S.)Median SalaryEmployed (U.S.)
Professional, Scientific, and Technical Services$138,9102K
Management of Companies and Enterprises$134,8802K
Administrative and Support Services$133,5506K
Finance and Insurance$133,3402K
Educational Services$132,8008K

Source: U.S. BLS OEWS National Industry-Specific estimates, May 2025. National figures (not state-specific).

Historical Salary Trend — Nurse Practitioner in South Carolina vs National

Historical Nurse Practitioner salary trend in South Carolina
YearMedian Salary (South Carolina)
2022$103,950
2023$112,510
2024$116,240
2025$123,290
2026 (projected)$130,687

The latest year is a projection based on recent wage trends — BLS has not yet released that year’s data.

Historical salary trend for Nurse Practitioner in South Carolina
YearSouth Carolina MedianNational Median
2022$103,950$118,452
2023$112,510$125,602
2024$116,240$129,125
2025$123,290$133,771
2026 (projected)$130,687$141,797

Nurse Practitioner Salary by Experience Level in South Carolina

Nurse Practitioner salary by experience level in South Carolina
Experience LevelYearsMedian Annual Salary
Junior0-2 yrs$107,930
Mid-level3-5 yrs$123,290
Senior6-9 yrs$132,220
Staff / Lead10+ yrs$160,170

Nurse Practitioner Salary in Other States

Related Nurse Practitioner Salaries in South Carolina

How other high-demand occupations in South Carolina compare to Nurse Practitioner ($123,290 median).

OccupationMedian Salaryvs Nurse PractitionerHourly
Internal Medicine Physician in SC$359,500+191.6%$172.84/hr
Emergency Medicine Physician in SC$341,960+177.4%$164.40/hr
Obstetrician and Gynecologist in SC$302,340+145.2%$145.36/hr
Nurse Anesthetist in SC$265,480+115.3%$127.63/hr
Family Medicine Physician in SC$239,200+94.0%$115.00/hr
Anesthesiologist in SC$238,970+93.8%$114.89/hr
Psychiatrist in SC$237,250+92.4%$114.06/hr
Pediatrician in SC$217,120+76.1%$104.38/hr
Radiologist in SC$174,480+41.5%$83.88/hr
Podiatrist in SC$167,110+35.5%$80.34/hr
Dentist in SC$158,640+28.7%$76.27/hr
Optometrist in SC$145,950+18.4%$70.17/hr

Frequently Asked Questions

What is the average salary for a Nurse Practitioner in South Carolina?

The median salary for Nurse Practitioners in South Carolina is $123,290 per year, which equates to approximately $59 per hour. This median figure is 7.8% lower than the national average for Nurse Practitioner salaries.

What is the salary range for Nurse Practitioners in South Carolina?

Nurse Practitioners in South Carolina can expect to earn within a range of $97,080 to $160,170 annually. The median salary falls right in the middle of this range at $123,290 per year.

How many Nurse Practitioners are employed in South Carolina?

There are approximately 5,670 Nurse Practitioners currently employed in South Carolina. This indicates a significant presence of these healthcare professionals within the state.

Is the Nurse Practitioner salary in South Carolina higher or lower than the national average?

The median Nurse Practitioner salary in South Carolina is 7.8% lower than the national average. While the median is $123,290 annually, the national median would be higher than this figure.

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